In Betty''s (Bettina Lamprecht) clinic, lives take a new turn — not only those of the patients, but also of Betty and her comrades-in-arms. At the eye of the "hurricane": the nurses'' room, Betty''s refuge and headquarters. Here Betty marshals her troops day after day against ignorance, multi-resistant hospital germs and lovesickness. Regularly recruited for the cause are the beautiful Lizzy (Theresa Underberg) and trainee nurse Talula (Carolin Walter). A real ray of light is Dr Marco Behring (Maximilian Grill); much of the female staff is smitten with the young ward doctor. So Betty and her "sisters" have to battle new and wildly varied challenges day after day. The leading roles are played by Bettina Lamprecht (2013 German Comedy Award for "Pastewka" and "Ladykracher", 2012 German Comedy Award for the "ZDF heute-show"), Maximilian Grill, Theresa Underberg and others.